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the designations for abnormal sex chromosome complements in the human female in which there are, respectively, three, four, or five instead of the normal two X chromosomes so that each somatic cell contains a total of 47, 48, or 49 chromosomes.Although there is no consistent phenotype associated with such aberrations, the risk of congenital anomalies and mental retardation in the affected individual increases significantly as the number of X chromosomes increases.
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The statue stands near the Leuvehaven, not far from the Erasmusbrug in the centre of the city, on the north shore of the river Nieuwe Maas.
Rotterdam was gradually rebuilt from the 1950s through to the 1970s.
In 1340 Rotterdam was granted city rights by the Count of Holland and slowly grew into a major logistic and economic centre.
Nowadays it is home to Europe's largest port and has a population of 633,471 (2014, city proper), ranking second in the Netherlands, just behind Amsterdam.
The city of Rotterdam is known for the Erasmus University, riverside setting, lively cultural life and its maritime heritage.
The near-complete destruction of Rotterdam's city centre during World War II (known as the Rotterdam Blitz) has resulted in a varied architectural landscape including sky-scrapers, which are an uncommon sight in other Dutch cities.
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The extensive distribution system including rail, roads, and waterways have earned Rotterdam the nickname "Gateway to Europe", and, conversely; "Gateway to the World" in Europe.
The settlement at the lower end of the fen stream Rotte (or Rotta, as it was then known, from rot, "muddy" and a, "water", thus "muddy water") dates from at least 900 CE.
On 7 July 1340, Count Willem IV of Holland granted city rights to Rotterdam, which then had approximately 2,000 inhabitants.